Occupational toxicology is the study of the adverse effects of agents that may be encountered by workers during the course of their employment. The adverse effects may be in the workers themselves, or in experimental animals, or other test systems used to define and/or understand the toxicity of the agent of interest. The term ‘occupational’ is used in preference to ‘industrial’ because the latter may have the connotation of chemical exposure in factories; this would not necessarily include work such as farming, with potential exposure to pesticides—or office work, with issues such as photocopiers in enclosed space.
Why is occupational toxicology required?
There is considerable public awareness of the health effects of chemicals due to events such as the thalidomide tragedy and environmental contamination with chemicals. Recognition of workplace exposures resulting in health effects has been part of this. A cursory glance at the Group 1 carcinogen list of the International Agency for Research on Cancer (IARC) should be evidence enough from this perspective. The epidemic of
asbestos-related cancer that continues in some countries, and which will become evident in others in the coming years, indicates that there is no room for complacency in our efforts to curb substance-related ill health.
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